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高妍

个人简历:  高妍, 2004年于辽宁科技大学获得应用化学专业硕士学位,2012年于天津大学获应用化学专业博士学位。现为辽宁科技大学化工学院副教授,先后主持并参与了多项辽宁省教育厅、鞍山市科技局、博士启动基金项目、校青年教师课题基金等多项科研项目,为企业和社会创造了经济效益。先后在国际、国内权威学术期刊发表论文20余篇,其中SCI收录论文16篇。
主要研究方向、成果及获奖情况:
1.重要农药、医药中间体的开发研制:主要是利用活性拼接原理,合成结构新颖的的有机杂环化合物,并对其生物活性进行深研究。
2. 化学发光材料的研发:合成新型的化学发光材料如三苯基咪***衍生物等,并深入研究其构效关系。
3. 新型荧光分子探针的研制:主要是设计合成结构新颖的有机杂环化合物,利用紫外和荧光光谱筛选出对金属离子具有高选择性的荧光分子探针,并对其识别机理进行深入探讨。
已取得的主要成果(主要发表论文、专利)

1. Wei Wang, Xiaolong Yu, Qiang Zhang, Mingzhu Li, Xiaoyu Jiang, Qinglei Liu, Yan Gao*, Synthesis and Fe3+ recognition of novel triazole Schiff-bases derivatives bearing fluorogenic naphthalene and anthracene units. Journal of Chemical Research, 2014,38,627-629.

2. Wei Wang , Wen-Jing Yuan , Qing-Lei Liu , Ya-Nan Lei , Shuai Qi  and Yan Gao *, Selective fluorescence sensor for Cu2+ with a novel triazole Schiff-base derivative with coumarin units. Heterocyclic Communication, 2015, 20(5), 289-292.

3. Wei Wang, Shuai Qi, Qing-Lei Liu, Ya-Nan Lei, Wen-Jing Yuan, Yan Gao,* Selective Zn2+ recognition of novel triazole Schiff-base derivatives bearing coumarin group. Journal of Chemical Research, 2014,38,604-606
4. Bing Zhao, Lili Jiang, Zhuo Liu, Qigang Deng, Liyan Wang, Bo Song ,Yan Gao*, Microwave-assisted Michael addition of 2-amino pyridine to chalcones under catalyst-free conditions. Res. Chem. Intermed. (DOI 10.1007/s11164-014-1703-9)
5. Bing Zhao, XuYu, Qi-GangDeng, ZhuoLiu, Li-YanWang, Yan Gao* , One-pot, three component synthesis of novel 5H-[1,3,4]thiadiazolo [3,2-a] pyrimidine-6-carboxylate derivatives by microwave irradiation. Tetrahedron Letters. 2014,55,4521-4524.
6. Wei Wang, Mingzhu Li, Xiaolong Yu, Qiang Zhang, Xiaoyu Jiang, Junwu Wang, Yan Gao* , Synthesis, Crystal Structure and Cu2+ Recognition of Novel Azobenzene Derivatives, Journal of Chemical Research, 2014,2,98-101.
7. Wei Wang , Junwu Wang , Xiaoyu Jiang , Kui Yang , Qiang Zhang ,Yan Gao*, Selective fluorescence sensing of ferric ion with novel triazolethione Schiff bases probes, Heterocyclic Communication, 2013, 19 (4) : 249-252 .
8. Wei Wang, Xiaoyu Jiang, Qiang Zhang, Mingzhu Li, Xiaolong Yu, Junwu Wang, Yan Gao*, Synthesis and Mercury ion recognition of novel azobenzene derivatives bearing naphthalene units, Journal of Chemical Research, 2013,11,662-664.
9. Bing Zhao, Lili Jiang, Zhuo Liu, Qigang Deng, Liyan Wang, Bo Song, Yan Gao*, A microwave assisted sythesis of highly substituted 7-methyl-5H-thiazolo [3, 2-a] pyrimidine-6-carboxylatederivatives via one-pot reaction of aminothiazole, aldehyde and ethyl acetoacetata, Heterocycles, 2013, 87(10): 2093-2102.

10. Bing Zhao, Yaoyu Ruan, Mingjie Ma, Qigang Deng, Liyan Wang, Yaqing Feng, Yan Gao*, One-pot synthesis of 11, 23-bis(imidazol-1-yl)calix [4]arene derivatives based on the upper rim of bisaminocalix[4] arene, Heterocycles, 2013, 87(9):1917-1924.

11. Yan Gao, Jian Song and Wei Wang, Synthesis and Hg2+ recognition of novel azobenzene derivatives bearing heterocyclic units. Journal of Chemical Research, 2012.36(3):146-148.
12. Yan Gao, Jian Song* and Wei Wang*, A Novel Azobenzene-Based Fluorescent Sensor for Selective Detection of Mercury Ion, Letters In Organic Chemistry, 2011, 8: 749-751.
13.Yan Gao and Yan Don. 3- [3-Methyl-4-(3-nitrobenzylideneamino)-5-
sulfanylidene-4,5-dihydro-1H-1,2,4-triazol-1-yl]-1,3-diphenylpropan-1-one, Acta Crystallographica Section E. 2011, E67, O2482.
14. Yan Gao, Li-hua Zhang and He-wen Wang 3-(4-Amino-3-phenyl-5-sulfanylidene-4,5-dihydro-1H-1,2,4-triazol-1-yl)-3-(2-chlorophenyl)-1-phenylpropan-1-one, Acta Crystallographica Section E. 2011, E67, O1794.
15. Yan Gao, Lu Wang and Hewen Wang,3-(4-Amino-3-methyl-5-sul-
fanylidene-4, 5-dihydro-1H-1, 2, 4-triazol-1-yl)-3-(2-furyl)-1-phenylpr-
opan-1-one, Acta Crystallographica Section E. 2011, E67, O1609.
16. Yan Gao, 2-(2-Pyridylsulfanyl)-N-p-tolylacetamide, Acta Crystallographica Section E.2008.
17. 高妍, 宋健. 微波辐射下1,2,4-三***硫酮席夫碱的合成及表征, 精细化工, 2012。( ★中文核心)
18. 高妍, 张志强等. 2-( 4’-2硝基苯基) 4 ,5-二( 3’-硝基苯基)咪***合成及机理研究, 化工新型材料, 2005, 33(12):42-44. ( ★中文核心)
19. 高妍, 张志强等. 间二氨基苯偶酰的合成, 化学试剂, 2005, 27(10), 627~628; (★中文核心)
20. 高妍, 张志强等.芳基取代咪***衍生物荧光性能的研究,化工科技 2005,13(3):8-10.
21. 高妍, 张志强等.间二硝基苯偶酰的合成及构象异构研究,化工科技,2005 ,13 (6) :8-10
专利:张志强,高妍等.《一种3-取代苯基吲哚化合物的微波合成方法》, 2009.2, 专利申请号【ZL200710010549.9】。★发明专利。
科研项目
1. 鞍山市科技局“噻***并嘧啶衍生物的绿色合成及抗菌活性研究”项目负责人,2014-2016
2.博士启动基金“新型荧光分子探针的设计合成和性能研究”项目负责人,2012-2014
3. 横向项目:新型浮选药剂的合成。项目负责人,2008-2009
4. 青年教师课题基金“噻嗪硫醚衍生物的合成及其抑菌活性研究”,项目负责人,2008-2010
5. 辽宁省科技厅“微波促进钯催化吲哚的3位直接芳基化反应”,第一参加人。2009-2010
6. 辽宁省科技厅 “不对称酰胺硫醚的合成及生物活性研究”,第一参加人。
7. 辽宁科技大学大学生科研训练计划“杂环硫乙酰氨基芳烃衍生物的合成及生物活性研究”,项目负责人,2008-2009